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Dosage and administration
For intramuscular use.
Cattle: The recommended dose is 0.150 mg d-cloprostenol per animal, equivalent to 2 ml per animal.
Oestrus induction (also in cows with weak or silent heat): After determining the presence of corpus luteum (day 6-18 of the cycle), administer the product. Heat is generally observed in 48-60 hours. Inseminate 72-96 hours after this treatment. If heat is not observed, repeat after 11 days.
Parturition induction: Administer the product after day 270 of gestation. Parturition should occur 30-60 hours post-treatment.
Oestrus synchronisation: Administer the product twice (11 days apart). Inseminate artificially at 72 and 96 hours after the second injection.
Ovarian dysfunction: Once the presence of corpus luteum is determined, administer the product and inseminate in the first heat after the treatment. If no heat is observed, carry out a gynaecological examination again and repeat the injection 11 days after the first treatment. Inseminate at 72-96 hours post-treatment.
Endometritis or pyometra: Administer 1 dose of the product. Repeat the treatment 10-11 days later if necessary.
Gestation interruption: Administer the product during the first half of gestation.
Foetal mummification: Administer 1 dose of product. The foetus will be expelled after 3 or 4 days.
Retarded uterine involution: Administer 1 dose of the product and, if indicated, repeat the treatment once or twice at 24 hour interval.
Pigs: The recommended dose is 0.075 mg d-cloprostenol per animal, equivalent to 1 ml per animal.
Parturition induction: Administer the product after day 112 of gestation. Repeat after 6 hours. Alternatively, 20 hours after the initial dose of d-cloprostenol, a myometrial stimulant (oxytocin or carazolol) may be administered. Following the protocol of double administration, in about 70% of cases, parturition occurs 20-30 hours after the first treatment.