Do not use in cases of hypersensitivity to the active substance or to any of the excipients.
Do not use in animals with spastic respiratory or gastrointestinal disease.
Do not use in gestating animals unless it is desirable to induce parturition or the interruption of pregnancy.
As with parenteral administration of any substance, basic aseptic rules should be observed. The injection site must be thoroughly cleaned and disinfected in order to reduce the risk of infection with anaerobic bacteria.
Occurrence of anaerobic infection is likely if anaerobic bacteria penetrate the tissue of the injection site. This applies especially to intramuscular injection and in particular to cows. Typical local reactions due to anaerobic infection are swelling and crepitus at the injection site.
Do not use in animals being treated with non-steroidal anti-inflammatory drugs, as the synthesis of endogenous prostaglandins is inhibited.
The activity of other oxytocic agents can be increased after the administration of cloprostenol.
Pigs: only use when the precise date of insemination is known. Administer on day 113 of gestation at the earliest. Administration of the product earlier may impair the viability and weight of the piglets.
Cattle: meat and offal: 1 day. Milk: zero hours.
Pigs: meat and offal: 1 day.
d-Cloprostenol, like all F2α prostaglandins, can be absorbed through the skin and can produce bronchospasm and abortion.
Women of child-bearing age, asthmatics and persons with bronchial problems or any other type of respiratory problem must avoid any contact or use disposable plastic gloves when administering the product.
Do not eat, drink or smoke while handling the product.
The product must be handled carefully to avoid accidental self-injection or skin contact.
In case of accidental self-injection seek medical advice and show the label to the physician. Seek medical advice immediately in case of any respiratory difficulty caused by accidental inhalation or inoculation. In case of accidental skin contact, wash with soap and water immediately.