A freeze-dried fraction containing live attenuated feline enteritis (panleucopaenia) virus (FPV), Snow Leopard strain, minimum titre 103.0 CCID50, live attenuated feline rhinotracheitis virus (FVR), strain FVRm, minimum titre 105.0 CCID50 and live attenuated feline calicivirus (FCV), strain F9, minimum titre 105.5 CCID50, supplied with a vial of water for injection for reconstitution.

For the active immunisation of healthy cats to reduce mortality and clinical signs of disease caused by feline enteritis (panleucopaenia) virus, to reduce clinical signs of disease caused by feline rhinotracheitis virus, and to prevent clinical signs of disease and reduce infection caused by feline calicivirus.

Onset of immunity occurs by approximately 3 weeks after the last dose of the Basic Vaccination Scheme.

The duration of immunity is at least 12 months.

Reconstitute the freeze-dried vaccine aseptically with the entire contents of the diluent provided. Shake and immediately inject the contents of the vial subcutaneously, 1 ml per dose.

In cats aged nine weeks and over, two injections of Versifel CVR, 3 to 4 weeks apart will stimulate full active immunity.

A single 1 ml dose is required on an annual basis.

For concurrent vaccination with Versifel FeLV, a single dose of Versifel CVR should be administered as described above. A single dose of Versifel FeLV should then be administered at a separate site via the subcutaneous route.

For simultaneous vaccination with Versifel FeLV, the contents of a single vial of Versifel CVR should be reconstituted with the contents of a single vial of Versifel FeLV in place of the diluent. Once mixed, the contents of the vial should appear as a slightly coloured (pink/orange) opaque suspension; the mixed vaccines should be injected immediately via the subcutaneous route.

Do not use chemically sterilised syringes or needles, as these might affect the response of the vaccine.

Vaccinate healthy animals only. Do not use in pregnancy.

On rare occasions, transient increases in rectal temperature, transient lameness and transient lethargy may be observed as well as soft painless swellings (<1 cm average) may occur in the first 24 hours after vaccination, which may be evident as painless hard nodules for up to 21 days after dosing.

On very rare occasions, an anaphylactic reaction may occur which may require appropriate symptomatic treatment (e.g. adrenaline).

When administered concurrently or simultaneously with Versifel FeLV transient increases in temperature (up to 40.5°C) are common following first vaccination lasting up to 5 days.

No reactions other than those listed above have been observed after an accidental overdose.

The feline panleucopaenia virus and the feline calicivirus vaccinal strains may be shed from vaccinated animals for a number of days following vaccination. However, due to the low pathogenicity of these strains it is not necessary to keep vaccinated animals separated from non-vaccinated animals.

Moderate to high levels of maternally derived antibodies (MDA) may interfere with the response to vaccination.

In case of accidental self-injection, wash the area immediately with water. If symptoms develop, seek medical attention showing a copy of the product literature.

Store and transport refrigerated (2°C - 8°C). Do not freeze.

Safety and efficacy data are available which demonstrate that this vaccine can be mixed with, or administered concurrently with Versifel FeLV. Do not mix with any other veterinary medicinal product.

Safety and efficacy data are available which demonstrate that this vaccine can be either mixed with Versifel FeLV and administered at a single site or administered on the same day as Versifel FeLV, but at different sites.

No data are available on the duration of immunity of Versifel CVR when administered together with Versifel FeLV, this should be taken into account when considering re-vaccination intervals.

No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product except the product mentioned above. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.

For animal treatment only.

Keep out of sight and reach of children.

Versifel CVR is supplied in cartons of 25 vials containing the freeze-dried fraction, together with 25 vials of the diluent. Packs of disposable syringes with needles are also available.