Do not use in animals with serious kidney (accompanied by anuria and oliguria) and/or liver failure.
Do not use in animals with known hypersensitivity to betalactamins.
The use of the product is contraindicated when a resistance to amoxicillin is known. Do not use in the presence of β-lactamase producing bacteria.
Do not administer to rabbits, guinea-pigs, hamsters or gerbils.
Special warnings
Animals with reduced feed intake and/or disturbed general condition have to be treated parenterally
Special precautions for use
Special precautions for use in animals
Animals with distinctive clinical signs of streptococcosis require individual treatment.
Use of the veterinary medicinal product should be based on susceptibility testing and take into account official and local antimicrobial policies. Inappropriate use of the veterinary medicinal product may increase the prevalence of bacteria resistant to amoxicillin. This drug premix is intended for the preparation of solid drug feed and cannot be used as is; the concentration of incorporation of the drug premix in solid feed must not be lower than 5 kg/ton.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
When feed is being prepared, avoid skin contact.
Whilst handling the product, wear a mask, coveralls, protective goggles and gloves at all times.
Avoid inhalation of dust. Wear either a disposable half-mask respirator conforming to European Standard EN149 or a non-disposable respirator to European Standard EN140 with a filter to EN143.
To rule out any risk of ingestion it is recommended not to eat, or drink while using the product and to wash the hands after use.
Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross-reactions to cephalosporins and vice versa. Allergic reaction to these substances may occasionally be serious.
1. Do not handle this product if you know you are sensitised, or if you have been advised not to work with such preparations.
2. Handle this product with great care to avoid exposure taking all recommended precautions.
3. If you develop symptoms following exposure, such as a skin rash, you should seek medical advice and show the doctor this warning. Swelling of the face, lips or eyes or difficulty in breathing are more serious symptoms and require urgent medical attention.
Adverse reactions (frequency and seriousness)
Gastrointestinal signs may sometimes be observed (diarrhoea).
Penicillins may cause allergic reactions after the administration of the product. Allergic reactions to these substances may sometimes be severe (anaphylaxis).
Use during pregnancy, lactation or lay
Laboratory studies have not produced any evidence of teratogenic, embryotoxic or maternotoxic effects of amoxicillin. Nevertheless, no study was performed in the target species during pregnancy or lactation. Therefore, use only accordingly to the benefit/risk assessment by the responsible veterinarian.
Interaction with other medicinal products and other forms of interaction
Do not administer together with bacteriostatic anti-infectious agents (tetracyclines, sulphonamides…). Do not use simultaneously with neomycin as it prevents the absorption of oral penicillins
Overdose (symptoms, emergency procedures, antidotes), if necessary
Apart from allergic reactions, penicillins have minimal direct toxicity.
There is no antidote, in case of accidental overdosage, the treatment is symptomatic.
Withdrawal period(s)
Meat and offal: 5 days
Incompatibilities
In the absence of compatibility studies, this veterinary medicinal product must not be mixed with other veterinary medicinal products.