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Tablets for oral administration containing cephalexin (as cephalexin monohydrate PhEur) in three strengths:
Rilexine 75 containing 75mg cephalexin
Rilexine 300 containing 300mg cephalexin
Rilexine 600 containing 600mg cephalexin
Cephalexin monohydrate is a bactericidal antibiotic of the cephalosporin family, obtained by hemi-synthesis of the 7 amino-cephalosporanic nucleus.
Cephalexin acts by inhibiting the nucleopeptide synthesis of the bacterial wall. As a result bacterial destruction occurs. Cephalexin is not inactivated by β-lactamases produced by the Gram positive bacteria and which normally affect penicillins.
After oral administration, Cephalexin is absorbed through the intestinal barrier. The plasma peak is observed very quickly (T max. 1.5). Therapeutic skin levels are obtained within 2 hours.
Cephalexin is eliminated as an active form, mainly by the urinary route (85%).
Cephalexin is effective against a wide range of Gram positive and Gram negative bacteria including: Staphylococci, Streptococcus spp., Pneumococci, E. Coli, Klebslella spp, and Salmonella spp.