Horses, ponies, donkeys and foals over four weeks of age.

Indications for Use, Specifying the Target Species

A broad spectrum anthelmintic for use in horses and donkeys for the control and treatment of adult infections of large and small strongyles, Oxyuris, Parascaris and Anoplocephala perfoliata.

Effective against benzimidazole resistant strains of small strongyles.

Not for use in horses with known hypersensitivity to the active ingredient.

Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:

Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.

Underdosing, which may be due to underestimation of body weight, misadministration of the product, or lack of calibration of the dosing device.(if any)

Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintics belonging to another pharmacological class and having a different mode of action should be used.

Resistance to pyrantel has been reported in cyathostomes in horses (also widespread in the US and Canada). Therefore the use of this product should be based on a local (regional, farm) epidemiological information about susceptibility of nematodes and recommendations on how to limit further selection for resistance to anthelmintics.

The same oral doser should only be used to dose two animals if they are both healthy and are either running together, or are on the same premises and in direct contact with each other.

Only for direct oral administration.

Avoid contact with skin. Wash hands and any other parts of the body which come into contact with the product.

Impaction of the small intestine may occur in foals, infected with high numbers of Parascaris equorum. Symptoms (colic) may be seen as soon as 30 minutes after treatment.

The product is specifically recommended for use in mares which may be pregnant and/or lactating.

No adverse effects have been found or reported in trials using higher than recommended dosages.

Combined administration of pyrantel and levamisole or piperazine is not recommended.

Strongid-P Paste is recommended for direct oral administration in horses, ponies, donkeys and foals over four weeks of age. It is not necessary to withhold any feed prior to administration. The following method of administration is recommended:

1. Position the locking ring over the appropriate mark on the plunger.

2. Remove the cap from the nozzle.

3. The paste is best deposited on the upper surface of the tongue. Introduce the nozzle end of the oral doser at the corner of the mouth. Direct the oral doser backwards and depress the plunger to deposit the paste onto tongue. Providing the paste is given in this way it is unlikely that any rejection will occur. Raising the head by a hand under the chin sometimes helps with swallowing.

For the control and treatment of strongyles Oxyuris and Parascaris but excluding Anoplocephala (tapeworm). Strongid-P Paste should be used at a dose rate of 19 mg pyrantel embonate per kg bodyweight.

Bodyweight range	Dose – contents of	Dose of pyrantel embonate
Up to 150kg	¼ oral doser	2.85g
151 – 300kg	½ oral doser	5.70g
301 – 450kg	¾ oral doser	8.55g
451 – 600kg	Full oral doser	11.40g

Note: Position locking ring over appropriate mark on plunger.

Strongyles. Oxyuris and Parascaris.

Foals: one to eight months of age - dose every four weeks.

Horses and donkeys: over eight months of age - routinely dose every six to eight weeks, but during the summer and autumn when horses and donkeys are at grass, dose every four to six weeks. Always dose three to four days before turning out after in-wintering.

Suckler mares: It has been shown that reduction of strongyle challenge to the suckling foal at pasture can be achieved by using clean pasture (re-seeded, or not grazed the previously year by horses), dosing the mare three to four days before turning out and then at intervals of two to four weeks until the end of autumn.

Ideally mares with foals should go out to “clean” pasture or, if this is not possible delay, turning them out until June.

Dosage: For the control and treatment of tapeworms: Strongid-P Paste should be used at a dose rate of 38 mg pyrantel embonate per kg bodyweight, that is twice the dose rate for strongyles.

Dosing programme – Tapeworm: The need for re-treatment may vary, but if considered necessary should be carried out after an interval of six weeks.

To ensure administration of a correct dose, body weight should be determined as accurately as possible; accuracy of the dosing device should be checked.

The product has an extremely wide safety margin and overdosage should not produce any adverse reactions.

Horse meat: zero days.