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Dosage and administration
Oromucosal use.
The product should be administered onto the oral mucosa between the dog’s cheek and gum at a dose of 125 micrograms/m2. The Sileo oral syringe is capable of delivering the product in 0.25 ml increments. Each increment is shown as one dot on the plunger. The dosing table provides the number of dots to be administered corresponding to the dog’s bodyweight.
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The following dosing table provides the dose volume (in dots) to be administered for the corresponding bodyweight. If the dose for the dog is more than 6 dots (1.5 ml), half of the dose should be administered to the oral mucosa on one side of the dog’s mouth and the other half of the dose onto the other side. Do not exceed the recommended dose.
Bodyweight of dog (kg)
Number of dots
2.0 - 5.5
1 °
5.6 - 12
2 ° °
12.1 - 20
3 ° ° °
20.1 - 29
4 ° ° ° °
29.1 - 39
5 ° ° ° ° °
39.1 - 50
6 ° ° ° ° ° °
50.1 - 62.5
7 ° ° ° ° ° ° °
62.6 - 75.5
8 ° ° ° ° ° ° ° °
75.6 - 89
9 ° ° ° ° ° ° ° ° °
89.1 - 100
10 ° ° ° ° ° ° ° ° ° °
The first dose should be given as soon as the dog shows the first signs of anxiety, or when the owner detects a typical stimulus (e.g. sound of fireworks or thunder) for eliciting anxiety or fear in the respective dog. Typical signs of anxiety and fear are panting, trembling, pacing (frequent change of place, running around, restlessness), seeking people (clinging, hiding behind, pawing, following), hiding (under furniture, in dark rooms), trying to escape, freezing (absence of movements), refusing to eat food or treats, inappropriate urination, inappropriate defecation, salivation, etc.
If the fear eliciting event continues and the dog shows signs of anxiety and fear again, re-dosing can be done when 2 hours has passed from the previous dose. The product can be dosed up to 5 times during each event.
Instructions for dosing the gel:
Dosing should be performed by an adult.
New oral syringe set up before first dosing:
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1. WEAR GLOVES
Wear impermeable disposable gloves when handling the veterinary medicinal product and handling the oral gel.
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2. HOLD PLUNGER
Hold the oral syringe so that you can see the dot markings on the oral syringe plunger. Hold the plunger with your left hand.
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3. UNLOCK
Hold the plunger with your left hand and unlock the green ring-stop by turning it towards you until it is able to slide freely.
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4. MOVE RING
Move the ring-stop to the opposite end of the plunger.
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5. LOCK
Hold the plunger with your right hand and lock the ring-stop by turning it away from you.
Dose selection and dosing:
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6. UNLOCK
Hold the plunger with your right hand and unlock the ring-stop by turning it towards you. Do not pull the plunger!
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7. MOVE RING
Move the ring-stop towards the other end of the plunger for choosing the correct dose based on your veterinarian's prescription.
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8. SET DOSE AND LOCK
Position the ring-stop so that the side nearest the barrel is in line with the graduation mark (black line), and the required number of dogs shows between the ring-stop and the barrel. Lock the ring-stop by turning it away from you. Before dosing make sure that the ring-stop is locked.
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9. PULL CAP (TIGHT)
Pull the cap strongly while holding the barrel. Note the cap is very tight (pull, do not twist). Save the cap for replacement.
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10. DOSE INTO CHEEK
Place the oral syringe tip between the dog's cheek and gum and press the plunger until the ring-stop causes the plunger to stop.
IMPORTANT: The gel should not be swallowed. If the gel is swallowed, it may not be effective.
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NOT SWALLOWED
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11. BACK TO PACKAGE
Recap the oral syringe and return it to the outer package as the product is sensitive to light. Make sure that the carton is closed properly. Keep the package out of sight and reach of children at all times. Remove and discard gloves.