In drinking water use and in-feed use in pigs.
In drinking water use in chickens.
Chickens:
The recommended dosage is 16 mg amoxicillin trihydrate per kg body weight per day (corresponding to 14 mg amoxicillin/kg, or 20 mg of the product/kg) administered in the drinking water, for 3-5 days.
Pigs:
The recommended dosage is 16 mg amoxicillin trihydrate per kg body weight per day (corresponding to 14 mg amoxicillin/kg, or 20 mg of the product/kg), for 3-5 days.
For the preparation of medicated water the body weight of the animals to be treated and their actual daily water consumption should be taken into account. Consumption may vary depending on factors like species, age, state of health, breed and husbandry system (e.g. different temperature, different light regimes). In order to obtain the correct dosage the concentration of amoxicillin has to be adjusted accordingly.
The following formula may be used to calculate the required amount of veterinary medicinal product in mg per litre of drinking water:
To ensure a correct dosage, body weight should be determined as accurately as possible to avoid underdosing.
The use of suitably calibrated weighing scales is recommended for measuring the calculated amount of the product.
Bolus dosage: It is recommended to administer the product once daily via the drinking water for a limited period of time. Restrict access to the drinking water system for approx. two hours (shorter time in warm weather) until the time of medication. Scatter the calculated daily quantity of powder on the surface of 5-10 litres water. Mix thoroughly until the powder has dissolved. Mix this solution by stirring into the volume of drinking water that will be consumed within about 2 hours. Maximum solubility of the product in water is approximately 8 g/L at room temperature (approximately 20 °C). The maximum solubility can be considerably reduced at lower temperatures. The complete dissolution of the powder should be ensured.
Continuous treatment: Preparation of medicated water should provide an amount to be consumed within the next 12 hours. Any unused medicated water should be discarded after 12 hours, and freshly medicated water for the next 12 hours should be prepared. The maximum concentration of the pre-diluted medicated water is approximately 8 g/L at room temperature (approximately 20 °C). The maximum solubility can be considerably reduced at lower temperatures. The complete dissolution of the powder should be ensured. The proportioner setting should be changed accordingly. In target animal species, water uptake may vary due to various factors, including environmental temperature, age and type of feed.
Make sure the animals do not have access to non-medicated water during the period when the medicated water is given. When all medicated water has been consumed, turn on the normal water supply again. After the end of the medication period the water supply system should be cleaned appropriately to avoid intake of sub-therapeutic amounts of the active substance.
In-feed use in pigs: The product may also be offered via the feed at the recommended daily dose. This way of administration is only intended for the treatment of individual pigs on farms where only a small number of pigs are to receive the treatment. Only the pack size of 100 g is suitable for the in-feed use. Larger groups should be treated with medicated drinking water.
Before each administration the powder should be thoroughly mixed into a small amount of food and should be given directly to the animal before the main ration. Care should be taken to ensure complete consumption of all medicated feed prior to providing the remainder of the daily feed ration.