Oral use.
Hens/Chickens:
1.43 mg flubendazole (= 14.3 mg veterinary medicinal product) per kg body weight daily via oral administration during 7 days i.e. 1 g of the veterinary medicinal product per 70 kg body weight daily for 7 days.
Pigs:
a) Treatment of helminthiasis caused by Ascaris suum (adult stages and intestinal larval stages):
1 mg flubendazole (= 10 mg veterinary medicinal product) per kg body weight daily via oral administration during 5 days, i.e. 1 g of the veterinary medicinal product per 100 kg body weight daily for 5 days.
b) Treatment of helminthiasis caused by Ascaris suum (adult stages):
2.5 mg flubendazole (= 25 mg veterinary medicinal product) per kg body weight daily via oral administration during 2 days, i.e. 2.5 g of the veterinary medicinal product per 100 kg body weight daily for 2 days.
Pigs should be grouped according to their bodyweight and dosed accordingly, in order to prevent under or overdosing.
Based on the recommended dose and the number and weight of animals to be treated, the exact daily concentration of the veterinary medicinal product should be calculated according to the following formula:
Calculate the dosage accurately with the following formula:
This will result in a concentration of flubendazole between 20 and 200 mg per litre.
Method of administration:
Administration in drinking water
1) The required quantity of the veterinary medicinal product is in function of the estimated body weight of the total group animals (see table below for guidance).
Hens/Chickens, 7 days of treatment:
|
Total weight of chickens | Amount of medication to be used (g/day) | Total amount of medication used (g/7 days) |
1400kg | 20g | 7 x 20g |
3500kg | 50g | 7 x 50g |
7000kg | 100g | 7 x 100g |
35000kg | 500g | 7 x 500g |
52500kg | 750g | 7 x 750g |
Pigs, 5 days of treatment:
| | |
Total weight of pigs | Amount of medication to be used (g/day) | Total amount of medication used (g/5 days) |
2000kg | 20g | 5 x 20g |
5000kg | 50g | 5 x 50g |
10000kg | 100g | 5 x 100g |
50000kg | 500g | 5 x 500g |
75000kg | 750g | 5 x 750g |
Pigs, 2 days of treatment:
| | |
Total weight of pigs | Amount of medication to be used (g/day) | Total amount of medication used (g/2 days) |
800kg | 20g | 2 x 20g |
2000kg | 50g | 2 x 50g |
4000kg | 100g | 2 x 100g |
30000 | 750g | 2 x 750g |
40000kg | 1000g | 2 x 1000g |
2) Each day a predilution is prepared containing the daily required dose of the veterinary medicinal product admixed in 10 to 100 times its weight in water depending on the distribution system. For example: for 500 g of the veterinary medicinal product, add 5 litres to 50 litres of water.
3) Squeeze the sachet gently before use and then empty the contents into the predilution recipient.
4) If less than entire sachet is required, the required dose should be measured by suitably calibrated weighing equipment.
5) Stir the predilution vigorously with a manual mixer (whisk) for 2 minutes to obtain a white milky homogenous mixture.
6) This predilution must be distributed via the general water supply system:
Tanks: add the predilution to the quantity of water usually consumed by the animals over a period of up to 4 hours.
Dosing pumps: adjust the flow rate of the pump to distribute the predilution over a period of up to 4 hours.
In order to ensure administration of the correct dose, a substantial water flow must be present in the drinking water system. Administration of the product over a period of up to 4 hours on each treatment day, at times when water consumption is likely to be highest prevents precipitation of flubendazole in the water delivery system and allows washing out of the drinking water system within a 24 hour period after the period of drug administration is finished.
7) Prior to and after the period of treatment make sure the water distribution system is cleaned.
8) Make sure that all animals in the group receive enough drinking water with the product. Withhold drinking water for 2 hours before treatment to stimulate thirst.
9) The corresponding dose must always be distributed when the water consumption of the animals is highest.
Use during pregnancy, lactation or lay
Laboratory studies in rabbits and rats have not produced any evidence of embryotoxicity, teratogenicity at therapeutic doses. High dosages gave equivocal results. In laboratory studies in rats, there were no effects on pups during lactation. The safety of the product has been demonstrated in laying hens, pregnant and lactating sows.
Pregnancy and lactation: Can be used in pregnant and lactating sows.
Laying birds: Can be used in laying hens.