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Contra-indications, warnings, etc
Do not use in cases of known hypersensitivity to the active substance or to any of the excipients.
Adverse reactions: Some cases of hypersensitivity reactions (anaphylactic-type reactions) have been described.
Special warnings: Administer by slow intravenous injection.
The formation of prothrombin may be inadequate when dealing with patients with severe liver dysfunction. Therefore requires a careful monitoring of coagulation parameters after administration of vitamin K1.
The safety of the veterinary medicinal product has not been established in bitches during pregnancy and lactation. Studies conducted in laboratory animals have shown no teratogenic or fœtotoxic effects. Vitamin K1 crosses the placental barrier. Use only accordingly to the benefit/risk assessment by the responsible veterinarian.
Special warnings for each target species:
As the anticoagulant effects of rodenticides are known to be long lasting it is recommended to start vitamin K1 supplementation with an oral formulation within 12 hours of the last injection for a duration of 3 weeks, and to evaluate the coagulation status (via one stage prothrombin times) 48 hours after the last administration. In the case of persistence of the anticoagulant in the body, the duration of treatment can be extended as long as the anticoagulant persists, to avoid relapse (the coagulation status has to be evaluated 48 hours after each attempt of treatment cessation).
User precautions: People with known hypersensitivity to phytomenadione should avoid contact with the veterinary medicinal product.
Avoid contact with eye. In the event of accidental contact with eye, rinse immediately and thoroughly with tap water, then seek a doctor and show the label to the physician. In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician.