Target species
Horse.
Indications for use
For intra-articular and intravenous treatment of lameness caused by joint dysfunction associated with non-infectious synovitis.
Contraindications
Do not use in cases of joint infection.
Special precautions for use in animals
Radiographic evaluation should be carried out in cases of acute, severe lameness to ensure that the joints are free from serious fractures.
Adverse reactions
Transient mild swelling and/or heat has been reported in treated joints (2.7%). These self-limiting local signs resolve spontaneously within 48 hours and do not negate a successful therapeutic outcome.
Use during pregnancy and lactation
Safety in pregnant and lactating mares has not been documented. Use only according to the benefit/risk assessment by the responsible veterinarian.
Amounts to be administered and administration route
Intravenous use: 3 ml intravenously repeated at weekly intervals for a total of three treatments.
For single intra-articular injection: 3 ml (51 mg) intra-articularly into medium sized and large joints. Smaller joints such as intertarsal, tarsometatarsal and interphalangeal joints can be treated with a 1.5 ml dose (25.5 mg).
More than one joint may be treated at the same time.
Excess synovial fluid should be removed whenever possible prior to injection.
Remove product from refrigerator approximately 10 minutes before performing injection. The injection should be administered under strict aseptic conditions. Ensure removal of dirt, hair, topical medicaments and soap/antiseptic residues. Intra-articular injections should not be made through overlying skin that is infected, blistered, scurfed or otherwise compromised. A sterile dressing and clean bandage should be applied after injection, as appropriate for the particular joint treated.
Single dose syringes made ready for injection shall be used immediately. Any unused portion of a syringe is to be discarded.
Withdrawal periods
Meat and offal: zero days.