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Pharmacological particulars
Pharmacotherapeutic group: Antibacterials for systemic use, beta-lactam antibacterials, penicillins, penicillins with extended spectrum
ACTVet code: QJ01CA01
The product contains ampicillin (as the trihydrate) 250 mg per capsule.
It is recommended for the treatment and control of diseases in dogs caused by or associated with bacterial pathogens sensitive to ampicillin.
Ampicillin is a broad spectrum antibiotic of the penicillin group, which is in turn a member of the beta-lactam group. It is well absorbed after oral administration but bioavailability is reduced by food in the stomach.
The mode of action of beta-lactams involves interference with cell wall synthesis and are therefore more effective when the cell wall is growing. At high dose levels the penicillins have additional bactericidal effects within the bacterial cell and may affect dormant bacteria.
Ampicillin is bactericidal against a wide range of Gram-positive and Gram-negative bacterial pathogens found in dogs including the following, provided that they are sensitive to ampicillin:
Streptococcus spp., Pasturella haemolytica, P. multocida, Staphylococcus aureus and other pathogenic staphylococci (non β lactamase producing).