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Clinical particulars
Target species
Cattle, Horses, Sheep, Goats, Pigs, Dogs, Cats and Rabbits
Indications for use, specifying the target species
Treatment of dehydration of extracellular predominance. Treatment and prevention of perioperative hypovolaemia and haemorrhagic shock. Treatment of mild metabolic acidosis.
Do not use in animals with:
congestive heart failure, hyperkalaemia, hypercalcaemia, metabolic alkalosis, hyperhydration, severe metabolic or lactic acidosis, hepatic insufficiency, Addisons disease or hypernatraemia
Special warnings for each target species
Special precautions for use
Special precautions for use in animals
Do not use unless the solution is clear, free from visible particles, and the container is undamaged. A risk of thrombosis with intravenous infusion should be considered. Maintain aseptic precautions. This product does not contain an antimicrobial preservative. It is intended for single use only and any unused contents should be discarded.
The solution should be warmed to approximately to 37° C prior to the administration of large volumes, or if the administration rate is high, in order to avoid hypothermia.
The volume and infusion rate must be adapted to the clinical status of each animal.
Use of this solution requires monitoring of the clinical and physiological status of the animal especially in cases of:
- severe renal impairment,
- cardiac impairment
- sodium retention with oedema,
- treatments with corticosteroids and their derivatives.

Monitor serum potassium and serum calcium in treated animals, particularly potassium levels in cases at risk of hyperkalaemia, such as during chronic renal failure.
In animals with hepatic impairment, the product may not produce its alkalising action since lactate metabolism may be altered.
Do not inject intramuscularly.
ii. Special precautions to be taken by the person administering the veterinary medicinal product to animals
Adverse reactions (frequency and seriousness)
The use of the product can cause metabolic alkalosis, in cases of excessive administration or impaired metabolism of lactate.
Not known under normal conditions of use.
Where the product is used as a drug carrier, this can lead to other adverse events.
Use during pregnancy, lactation or lay
The safety of the veterinary medicinal product has not been established during pregnancy and lactation. Use only accordingly to the benefit/risk assessment by the responsible veterinarian.
Interaction with other medicinal products and other forms of interaction
Interactions linked to calcium. In case of concomitant blood transfusion, the product should not be administered with the blood in the same infusion set due to the risk of clotting. This veterinary medicinal product contains calcium. Do not add drugs to this solution that may bind (chelate) to calcium.
Amounts to be administered and administration route
Administer by intravenous infusion.
Management of dehydration including patients with mild metabolic acidosis
The amount of fluid and electrolytes to be administered should be calculated by adding the existing deficits to the ongoing maintenance requirements and any ongoing fluid losses (e.g. from ongoing vomiting, diarrhoea etc) estimated from the history of the animal, clinical examination and laboratory findings. To calculate the existing fluid deficit, the following equation should be used;
Fluid deficit (mls) = Percentage dehydration x Bodyweight (kg) x 10
(e.g. for a 10 kg dog with 5% dehydration the fluid deficit would be 5 x 10 x 10 = 500ml)
To calculate the ongoing maintenance requirement, the following equation should be used;
Maintenance for Cattle, Horses, Sheep, Goats, Pigs, Dogs and Cats (mls) = 50ml x Bodyweight (kg) per day
Maintenance of Rabbits (mls) = 75-100ml x Bodyweight (kg) per day
(e.g. for a 10 kg dog, the daily maintenance fluid requirement is 10 x 50 = 500ml)
The administration rate should be adjusted to each animal. The objective is to correct the deficit over 12 – 24 hours.

Prevention of peri-operative hypovolaemia
Administer at a rate of 5 – 10ml/kg/hr during anaesthesia
Treatment of hypovolaemic and haemorrhagic shock
Cattle, Horses, Sheep, Goats, Pigs, Dogs Rabbits; up to 90ml/kg/hr
Cats; up to 60ml/kg/hr
High infusion rates should not be continued for longer than 1 hour.
Overdose (symptoms, emergency procedures, antidotes), if necessary
In the presence of volume overload signs (e.g. restlessness, moist lung sounds, tachycardia, tachypnoea or coughing), treatment should involve administering diuretics and stopping the infusion.
An excessive infusion of product may cause metabolic alkalosis due to the presence of lactate ions.
Withdrawal period(s)
Meat and offal: zero days.
Milk: zero hours