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Date: Sunday, May 26, 2024 12:56

Description: Animalcare_UK_2SpotCol_RGB_vertical_Logo
Release 2.105
Aqupharm No. 18 Infusion
 
Species: Cats, Dogs
Therapeutic indication: Pharmaceuticals: Dietary supplements and fluid metabolites: Oral rehydration and fluid replacements
Active ingredient: Glucose, Sodium Chloride
Product:Aqupharm No. 18 Infusion
Product index: Aqupharm No. 18 Infusion
Incorporating:
Qualitative and quantitative composition
Active Ingredients
Sodium Chloride 0.18% w/v
Glucose Anhydrous 4.0% w/v
(or Glucose Monohydrate 4.4% w/v)
Ions
Sodium 30.0 mmol/l
Chloride 30.0 mmol/l
Also contains 150 calories per litre as glucose
For full list of excipients, see Pharmaceutical Particulars
Pharmaceutical form
Solution for infusion. A clear, colourless solution free from particulate matter.
Clinical particulars
Target species
Dogs and Cats.
Indications for use, specifying the target species
For maintenance therapy after the fluid balance has been restored. It can be used for the treatment of moderate/prolonged dehydration due to water loss, but in severe cases Aqupharm No. 1 (Sodium Chloride Injection BP) should be given before continuing with Aqupharm No. 18.
Contraindications
Sodium overload may occur in cases with myocardial and renal damage. It should also be appreciated that in the period following surgical interference or severe trauma there may be an inability to excrete excessive sodium.
Special warnings for each target species
In evaluating an animal for possible fluid therapy the state of hydration, electrolyte balance, acid-base balance, renal function and caloric balance should be considered. Evaluation will be based on history, physical examination and laboratory testing.
In animals with potassium deficiency it may be necessary to give additional oral potassium supplements.
Special precautions for use
Special precautions for use in animals
Before use, the bag should be inspected and rejected if the solution is not clear or if the inner container is damaged. The solution should be prewarmed to 37ºC to prevent hypothermia. Thrombosis of a chosen vein is always a possibility with intravenous infusion. If infusion is protracted then another vein should be selected after 12-24 hours.
Special precautions for the person administering the veterinary medicinal product to animals
Wash hands after use.
Other precautions
None.
Adverse reactions (frequency and seriousness)
Hypernatraemia (sodium overload) or an inability to excrete excessive sodium – see Overdose.
Use during pregnancy, lactation or lay
There are no contra-indications to use of this product during pregnancy and lactation.
Interaction with other medicinal products and other forms of interaction
Drugs should not be mixed in infusion containers or through the giving sets unless the components are of known compatibility. The user should refer to the manufacturer’s literature for any drug substance which he or she proposes to co-administer, and also to the Appendix of Drug Incompatibilities in the current edition of The Veterinary Formulary.
Pharmacological particulars
Pharmacotherapeutic group: Electrolytes with carbohydrates
ATC Vet Code: QB 05 BB 02
Pharmacodynamic properties
This product is an intravenous solution containing 30mmol/l of sodium, 30mmol/l of chloride and 150calories per litre of glucose. When administered intravenously it will provide maintenance fluid needs after fluid balance has been restored.
Pharmacokinetic properties
Pharmacokinetics cannot readily be applied to fluid therapy since most of the infused solution is predominantly water, which on infusion will become incorporated into water rich plasma.
Pharmaceutical particulars
List of excipients
Water for injections
Incompatibilities
Ampicillin; Benzylpenicillin sodium; Cloxacillin sodium; Heparin sodium; Noradrenaline acid tartrate; Sulphadiazine sodium; Tetracyclines.
Shelf life
Shelf-life of the veterinary medicinal product as packaged for sale: 2 years.
Special precautions for storage
Do not store above 25°C. For single use only; any remaining solution should be discarded. This product does not contain an antimicrobial preservative. Do not freeze.
Nature and composition of immediate packaging
Packaging Format 1 A colourless, flexible polyvinyl chloride (PVC) bag with a blue PVC twist off giving set port and a re-sealable additives port, containing 500 ml or 1000 ml clear colourless solution. PVC bags are overwrapped with HDPE
Packaging Format 2 A colourless, flexible polyvinyl chloride (PVC) bag with re-sealable polyisoprene/polycarbonate giving set and additive ports, containing 500ml or 1000ml clear colourless solution. PVC bags are overwrapped with polypropylene.
Pack sizes Cardboard box containing; 20 bags of 500 ml solution for infusion, 10 bags of 1000 ml solution for infusion
Not all pack sizes may be marketed.
Special precautions for the disposal of unused veterinary medicinal product or waste materials derived from the use of such products, if appropriate
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.
Marketing Authorisation Holder (if different from distributor)
Ecuphar NV
Legeweg 157-i
8020 Oostkamp
Belgium
Marketing Authorisation Number
UK Vm 32742/4021
Significant changes
Date of the first authorisation or date of renewal
Date: 7 June 1993
Date of revision of the text
Date: July 2015
Any other information
Legal category
Legal category: POM-V
GTIN
GTIN description:Aqupharm No.18 1000ml
GTIN:5055037400724
GTIN description:Aqupharm No.18 500ml
GTIN:5055037400717