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Date: Sunday, June 15, 2025 22:38

Release 2.227
WORMclear® Praziquantel 20mg Spot-On Solution for Cats
Species: Cats
Therapeutic indication: Pharmaceuticals: Endoparasiticides: Anthelmintics for cats, Tapeworm products
Active ingredient: Praziquantel
Product:WORMclear® Spot-On for Cats
Product index: WORMclear® Spot-On Cat
Incorporating:
Qualitative and quantitative composition
Active ingredients
Each 0.5ml pipette contains Praziquantel 20mg.
Excipients
Butylhydroxytoluene 0.5mg. For the full list of excipients, see below.
Pharmaceutical form
Spot-on solution. Clear, colourless to slightly reddish liquid.
Clinical particulars
Target species
Cats.
Indications for use
For the treatment of tapeworms in cats. The product is effective against mature and immature forms of Dipylidium caninum and Taenia species. The product is also effective against Echinococcus multilocularis.
Contraindications
Do not use on cats weighing less than 1kg. Do not use in cases of hypersensitivity to the active substance or to any of the excipients.
Special warnings for each target species
Do not allow recently treated animals to groom each other. Care should be taken to avoid the contents of the tube coming into contact with the eyes or mouth of the user or the recipient animal. Do not use if your cat is sick or recovering from illness. For external use only.
Special precautions to be taken by the person administering the veterinary medicinal product
This product can be irritant to the skin and eyes. Care should be taken to prevent contact of the solution with the skin or eyes. If contact with the skin occurs, wash off any skin contamination with soap and water immediately. If accidental contact occurs with the eyes, flush the affected eyes thoroughly with clean fresh water. In the event of skin or eye contact, seek medical advice if irritation persists and show the doctor this package. Do not stroke or groom animals until area of application is dry (typically around 1 hour after application). Wash hands thoroughly after use. Do not eat, drink or smoke during application. Store away from food, drink or animal feeding stuffs.
Adverse reactions
Occasionally a transient local reaction such as scurf or mild exudation may be observed at the application site following treatment. The product is bitter tasting and salivation may occasionally occur if the cat licks the application site immediately after treatment. This is not a sign of intoxication and disappears after a short time without treatment.
Use during pregnancy and lactation
There are no contraindications against use during pregnancy and lactation.
Interaction with other medicinal products
No incompatibility has been observed between this product at the recommended dose and a range of common veterinary treatments.
Dosage and administration
The minimum dose rate is 8mg/kg, which equates to 1 tube per 2.5kg body weight.
Body weight
Number of tubes
Quantity of Praziquantal
mg/kg body weight
1–2.5kg
1
20mg
8–20
2.5–5kg
2
40mg
8–16
≥5kg
3
60mg
Maximum 12
Remove one tube from the package. Hold tube in an upright position, twist and pull off cap. Use reversed cap to twist and remove seal from tube. Part the hair on the cat's neck at the base of the skull until the skin is visible. Place the tip of the tube on the skin and squeeze firmly several times to empty the contents directly onto the skin. Application at the base of the skull will minimise the opportunity for the cat to lick the product. To minimise the possibility of run off after application of more than one pipette, it is advised that the applications should be performed slowly to allow absorption and that it may be advisable to allow the contents of the previous pipette to be absorbed before applying another. Tapeworm infestation is certain to reoccur unless control of intermediate hosts such as fleas, mice etc. is undertaken. Flea control: flea infestations can be controlled by the regular use of effective flea control remedies. Mice control: if cats roam and hunt, contact with, and consumption of, mice and subsequent re-infestation with Taenia taeniaeformis is impossible to prevent. It is recommended to reapply the product when signs of tapeworm infestation reappear or at monthly intervals.
Overdose
Overdosing can lead to slight skin reactions which disappear without treatment within a few days.
Pharmacological particulars
Pharmacotherapeutic group: Anthelmintic: Quinoline derivatives and related substances. ATC vet code: QP52AA01
Pharmacodynamic properties
Praziquantel, the active ingredient, is a pyrazinoisoquinoline derivative used widely as an anthelmintic for both human and veterinary medicine. The chemical name for this substance is 2-cyclohexyl-carbonyl[1,2,3,6,7,11b] hexahydro-4H-pyrazino-[2,1-a]isoquinolin-4-one. Praziquantel is effective against all stages of development of intestinal tapeworms. The substance is very rapidly absorbed and distributed throughout the parasite. Both in vivo and in vitro studies have shown that praziquantel causes severe damage to the parasite integument, resulting in contraction and paralysis. There is an almost instantaneous tetanic contraction of the parasite musculature and a rapid vacuolisation of the syncytial tegument. This rapid contraction has been explained by changes in divalent cation fluxes, particularly calcium.
Pharmaceutical particulars
List of excipients
Butylhydroxytoluene, N-methylpyrrolidone.
Incompatibilities
None known.
Shelf life
Shelf life of the veterinary medicinal product as packaged for sale: 30 months.
Special precautions for storage
Store away from food, drink and animal feeding stuffs.
Nature and composition of immediate packaging
White opaque polypropylene tube with an integral nozzle and rupturable membrane. White polypropylene cap
Disposal
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.
Marketing Authorisation Holder (if different from distributor)
Vetoquinol UK Limited, Steadings Barn, Pury Hill Business Park, Nr. Alderton, Towcester, Northamptonshire, NN12 7LS
Marketing Authorisation Number
Vm 08007/4175
Significant changes
Date of the first authorisation or date of renewal
25 September 2014
Date of revision of the text
November 2020
Any other information
N/A.
Legal category
Legal category: AVM-GSL
GTIN
GTIN description:2 pipette pack
GTIN:08711231171910