metadata toggle
Dosage and administration
Each dose of 2ml contains:
Lyophilisate (Active substance): Live attenuated bovine respiratory syncytial virus (BRSV), strain Lym-56...104.7-6.5 CCID50*Cell Culture Infective Dose 50%
Solvent: Phosphate buffer solution.
Nasal or intramuscular use. Reconstitute the vaccine with the corresponding volume of solvent:
Number of doses in vial of lyophilisate
Volume of solvent to be used
5 doses
10ml
25 doses
50ml
1. Peel the top off the aluminium cap on the vial containing the solvent and withdraw 10ml
2. Inject the 10ml of solvent into the vial containing the lyophilisate (freeze-dried powder)
3. Shake until the freeze-dried powder is in suspension. The 5 dose vial is now ready to use.
4. For the 25 dose vial, once the freeze-dried powder is in suspension, withdraw all the suspension obtained from the vaccine vial and inject it into the vial containing the remaining solvent.
5. Shake well before use. The reconstituted vaccine is a slightly yellowish homogenous suspension.
Avoid contamination during reconstitution and use. Use only sterile needles and syringes for administration.
For nasal use, spray the required volume of the vaccine into the animal's nostrils (1ml in each nostril) using an intranasal applicator (droplet size: 25-220 μm). It is recommended to use a new applicator for each animal.
The following doses and administration methods should be used:
Cattle from 9 days of age:
Primary vaccination (nasal use): Spray 1 ml into each nostril (so the total volume administered is 2 ml)
Revaccination: One intramuscular injection of 2 ml should be given 2 months after the primary vaccination and then every 6 months after the last revaccination.
Cattle from 10 weeks of age:
Primary vaccination (intramuscular injection): One intramuscular injection of 2 ml should be given followed by a second intramuscular injection of 2 ml given 4 weeks later.
Revaccination: One intramuscular injection of 2 ml should be given 6 months after completion of the primary vaccination scheme and then every 6 months after the last revaccination.