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Pharmacological particulars
Pharmacotherapeutic group: Antiparasitic products, insecticides and repellents; Triclabendazole
ATC vet code: QP52 AC01
Pharmacodynamic properties
Triclabendazole is a flukicide.
Pharmacokinetic particulars
Majority of oral dose in rats, sheep, goats and rabbits is eliminated in faeces after 6-10 days, as unchanged drug or products of biliary excretion. Urinary excretion is minimal. Sulphone, sulphoxide, ketone and 4-hydroxy triclabendazole derivatives are the main metabolites identified in plasma.