metadata toggle
Pharmacological particulars
Pharmacotherapeutic group: Corticosteroids, moderately potent, other combinations
ATCvet code: QD07XB02
Pharmacodynamic properties
Triamcinolone acetonide in this concentration is a moderately potent steroid. Corticosteroids have an anti-inflammatory and vasoconstrictive action. They suppress the inflammatory response and the symptoms of various disorders often associated with itching. The treatment however does not cure the underlying diseases.
Salicylic acid has an acidifying effect and also has a cerumenolytic effect through its keratolytic properties.
Pharmacokinetic properties
Triamcinolone acetonide can be absorbed through the skin, and, although the concentration is low, a systemic action is not excluded. After systemic absorption, triamcinolone is 60-70% bound to plasma proteins. Triamcinolone is metabolised primarily in the liver. The main metabolite is 6β-hydroxytriamcinolone, which is excreted mainly in the form of sulfates and glucuronides in urine.