Target species
Horses (mares), cattle (cows), pigs (sows), sheep (ewes), goats (nanny), dogs (bitches) and cats (queen)
Indications for use, specifying the target species
In the mare, cow, sow, ewe, nanny, bitch and queen the product is indicated for:
∙ Obstetric use (stimulation of uterine contraction to facilitate parturition in the presence of a fully dilated cervix, promotion of involution of the post-partum uterus, aid in the control of post-partum haemorrhage).
∙ Promotion of milk let-down in cases of agalactia.
Contraindications
Do not use in cases of obstructive dystocia and/or in cases of non-dilatation of the uterine cervix.
Do not use in cases of hypersensitivity to the active substance or to any of the excipients.
Special warnings for each target species
Adrenaline at physiological levels markedly reduces the effect of Oxytocin on the uterus or mammary gland. For this reason the animal should not be frightened when complete Oxytocin effect is desired to cause either milk "let-down" or uterine contractions.
Special precautions for use in animals
When the veterinary medicinal product is used as an aid in parturition cervical dilation must be confirmed prior to administration to prevent risk of foetal death and possible uterine rupture.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
Pregnant or lactating women should avoid handling the product as it could cause smooth muscle (e.g. uterine) contraction.
When administering the product, care should be taken to avoid accidental self-injection.
In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician.
Adverse reactions (frequency and seriousness)
None.
Use during pregnancy, lactation or lay
The product is indicated for use, as appropriate, during parturition and lactation. Do not use during pregnancy except at the time of parturition.
Interaction with other medicinal products and other forms of interaction
This veterinary medicinal product maybe used concurrently with antibiotics in the treatment of endometritis.
Stimulation of β-adrenergic receptors may reduce oxytocin’s effects on the uterus and mammary gland.
If sympathomimetic agents or other vasoconstrictors are used concurrently with oxytocin, post-partum hypertension may result.
Amounts to be administered and administration route
Administered by subcutaneous or intramuscular injection.
Mare & Cow 4 – 6 ml
Sow 1 – 3 ml
Ewe & Nanny 1 – 2 ml
Bitch & Queen 0.25 – 1 ml
For treatment of agalactia the stated higher dosage level should be used.
The product may be administered by slow intravenous injection at dose rates one third of the above.
Enhanced dose rates will not result in proportionally increased pharmacological effects.
Overdose (symptoms, emergency procedures, antidotes), if necessary
Excessive doses of the veterinary medicinal product may delay parturition by producing uncoordinated uterine contractions which interfere with the progress of the foetus especially in multiple pregnancies.
Treatment of overdose is palliative and there are no specific antidotes.
Withdrawal period(s)
Meat and offal: zero days.
Milk: zero hours.