Cats and dogs:
For dogs and cats suffering from, or at risk from, mixed parasitic infections:
Flea treatment and prevention (Ctenocephalides felis): One treatment prevents future flea infestation for 4 weeks. Pre-existing pupae in the environment may emerge for 6 weeks or longer after treatment is initiated, depending upon climatic conditions. Therefore, it may be necessary to combine treatment with this veterinary medicinal product with environmental treatments aimed at breaking the flea life cycle in the surroundings. This can result in a more rapid reduction in the household flea population. Administer at monthly intervals when used as part of a treatment strategy for flea allergy dermatitis
Treatment of ear mite infestation (Otodectes cynotis): administer a single dose. Loose debris should be gently removed from the external ear canal at each treatment. A further veterinary examination 30 days after treatment is recommended as some animals may require a second treatment. Do not apply directly to the ear canal.
Cats:
Treatment of notoedric mange (Notoedres cati): Administer a single dose.
Treatment of the lungworm Eucoleus aerophilus (syn. Capillaria aerophila) (adults): Administer a single dose.
Prevention of Aelurostrongylus abstrusus: Administer a single dose monthly.
Treatment of Aelurostrongylus abstrusus: Administer monthly for three consecutive months.
Treatment of the eye worm Thelazia callipaeda (adults): Administer a single dose.
Heartworm prevention (Dirofilaria immitis): Cats in areas endemic for heartworm, or those which have travelled to endemic areas, may be infected with adult heartworms. For prevention of heartworm disease, the product must be applied at regular monthly intervals during the time of the year when mosquitoes (the intermediate hosts which carry and transmit heartworm larvae) are present. The product may be administered throughout the year or at least 1 month before the first expected exposure to mosquitoes. Treatment should continue at regular monthly intervals until 1 month after the last exposure to mosquitoes. To establish a treatment routine, it is recommended that the same day or date be used each month. When replacing another heartworm preventative product in a heartworm prevention programme, the first treatment with this product must be given within 1 month of the last dose of the former medication.
In non-endemic areas there should be no risk of cats having heartworm. Therefore they can be treated without special precautions.
Roundworm and hookworm treatment (Toxocara cati and Ancylostoma tubaeforme): In areas endemic for heartworm, monthly treatment may significantly reduce the risk of re-infection caused by the respective roundworms and hookworms. In areas non-endemic for heartworm, the product can be used as part of a seasonal prevention programme against fleas and gastrointestinal nematodes.
Dogs:
Treatment of sarcoptic mange (caused by Sarcoptes scabiei var. canis): Administer a single dose twice, 4 weeks apart.
Prevention of heartworm disease (D. immitis) and cutaneous dirofilariosis (skinworm) (D. repens): Dogs in areas endemic for heartworm, or those which have travelled to endemic areas, may be infected with adult heartworms. Therefore prior to treatment with the veterinary medicinal product, a risk –benefit analysis must be observed. For prevention of heartworm disease and cutaneous dirofilariosis, the product must be applied at regular monthly intervals during the time of the year when mosquitoes (the intermediate hosts which carry and transmit D. immitis and D. repens larvae) are present. The product may be administered throughout the year or at least 1 month before the first expected exposure to mosquitoes. Treatment should continue at regular monthly intervals until 1 month after the last exposure to mosquitoes. To establish a treatment routine, it is recommended that the same day or date be used each month. When replacing another heartworm preventative product in a heartworm prevention programme, the first treatment with this veterinary medicinal product must be given within 1 month of the last dose of the former medication. In non-endemic areas there should be no risk of dogs having heartworm. Therefore, they can be treated without special precautions.
Treatment of microfilariae (D. immitis): Administer monthly for two consecutive months.
Treatment of cutaneous dirofilariosis (skin worm) (adult stages of Dirofilaria repens): Administer monthly for six consecutive months.
Reduction of microfilariae (skin worm) (D. repens): Administer monthly for four consecutive months.
Treatment and prevention of Angiostrongylus vasorum: Administer a single dose. A further veterinary examination 30 days after treatment is recommended as some animals may require a second treatment. In endemic areas regular monthly applications will prevent angiostrongylosis and patent infection with Angiostrongylus vasorum.
Treatment of Crenosoma vulpis: Administer a single dose.
Prevention of spirocercosis (Spirocerca lupi): Administer monthly.
Treatment of Eucoleus (syn. Capillaria) boehmi (adults): Administer monthly for two consecutive months. It is advisable to prevent auto-coprophagia between the two treatments in order to prevent possible reinfection.
Treatment of the eye worm Thelazia callipaeda (adults): Administer a single dose.
Roundworm, hookworm and whipworm treatment (Toxocara canis, Ancylostoma caninum, Uncinaria stenocephala, Toxascaris leonina and Trichuris vulpis): In areas endemic for heartworm, monthly treatment may significantly reduce the risk of re-infection caused by the respective round-, hook- and whipworms. In areas non-endemic for heartworm, the product can be used as part of a seasonal prevention programme against fleas and gastrointestinal nematodes.
Studies have shown that monthly treatment of dogs will prevent infections caused by Uncinaria stenocephala.