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Pharmacological particulars
ATC Vet Code: QP53AC11
Pharmacotherapeutic group: pyrethroid ectoparasiticide for topical use
Pharmacodynamic properties
The product is an ectoparasiticide whose active ingredient deltamethrin belongs to the synthetic pyrethroids class. Its mode of action affects the neurotransmission in the target parasite.
Pharmacokinetic particulars
After dermal application, deltamethrin is slightly absorbed through skin of cattle and sheep and remains available to the target ectoparasite. The main route of excretion of the absorbed amount in the target animal is the faeces. In terms of residues, fat is the target issue.
Environmental properties
Deltamethrin is very toxic to dung fauna, aquatic organisms and honey bees. It is persistent in soils and may accumulate in sediments.
Deltamethrin has the potential to adversely affect non-target organisms, both in water and in dung. Following treatment, excretion of deltamethrin levels potentially toxic to dung fauna may take place over a period of 2 to 4 weeks. Faeces containing deltamethrin excreted onto pasture by treated animals may reduce the abundance of dung feeding organisms which may impact on the dung degradation.