Pharmacotherapeutic group: Antipsychotics.
ATCvet code: QN05AA04
Pharmacodynamic properties
Acepromazine is a phenothiazine. It is a central nervous system depressant with associated activity on the autonomic system. Phenothiazines have a central action due to inhibition of dopamine pathways, resulting in alteration of mood, reduction in fear and removal of learned or conditioned responses.
Acepromazine possesses anti-emetic, hypothermic, vasodilatory (and therefore hypotensive) and anti-spasmodic properties.
Pharmacokinetic properties
The length of action of acepromazine appears to be prolonged and to be dose dependent.