For single administration only (except for the treatment of Psoroptes ovis infections in sheep).
To ensure administration of a correct dose, bodyweight should be determined as accurately as possible. Accuracy of the dosing device should be checked.
If animals are to be treated collectively rather than individually, they should be grouped according to their bodyweight and dosed accordingly, in order to avoid under- or over-dosing.
Cattle
Dosage:
1.0 ml per 50 kg bodyweight (based on a recommended dosage level of 200 micrograms ivermectin per kg bodyweight).
Administration:
Inject subcutaneously in front of, or behind, the shoulder using aseptic technique. A sterile 1.4 x 15 mm (17G x ½ inch) needle is recommended.
Sheep
Dosage:
0.5 ml per 25 kg of bodyweight (based on a recommended level of 200 micrograms ivermectin per kg bodyweight).
Administration:
For the treatment of gastrointestinal roundworms, lungworms and nasal bots inject once subcutaneously in the neck, using aseptic precautions; a sterile 1.4 x 15 mm (17G x ½ inch) needle is recommended. For the treatment of Psoroptes ovis (sheep scab), two injections with a seven day interval are required to treat clinical signs of scab and to eliminate living mites.
For young lambs weighing less than 20.0 kg give 0.1 ml per 5 kg. In these lambs the use of a syringe which can deliver as little as 0.1 ml is recommended.
Pigs
Dosage:
1.5 ml per 50 kg bodyweight (based on a recommended dosage level of 300 micrograms ivermectin per kg bodyweight)
Administration:
The recommended route of administration is by subcutaneous injection into the neck using aseptic technique and a sterile 1.4 x 15 mm (17G x ½ inch) needle.
For piglets weighing less than 16 kg give 0.1 ml per 3 kg. In these piglets the use of a syringe which can deliver as little as 0.1 ml is recommended.
When using the 200 or 500ml pack sizes, use only automatic syringe equipment. For the 50ml pack size, use of a multiple dose syringe is recommended. To refill the syringe, use of a draw-off needle is recommended to avoid excessive broaching of the stopper.
Overdose (symptoms, emergency procedures, antidotes), if necessary
Clinical symptoms of ivermectin toxicity include ataxia and depression. No antidote has been identified. In case of overdose, symptomatic treatment should be given. No signs of toxicity were observed in animals treated at up to 3 times the recommended dose rate.