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Clinical particulars
Target species
Seresto Flea and Tick Control 1.25 g + 0.56 g, collar for cats
Cats
Seresto Flea and Tick Control 1.25 g + 0.56 g, collar for small dogs ≤ 8 kg
Dogs (≤ 8 kg)
Seresto Flea and Tick Control 4.50 g + 2.03 g, collar for large dogs > 8 kg
Dogs (> 8 kg)
Indications for use, specifying the target species
Cats
For the treatment and prevention of flea (Ctenocephalides felis) infestation for 7 to 8 months.
Protects the animal’s immediate surroundings against flea larvae development for 10 weeks.
The product can be used as part of a treatment strategy for the control of Flea Allergy Dermatitis (FAD), where this has been previously diagnosed by a veterinary surgeon.
The product has persistent acaricidal (killing) efficacy (Ixodes ricinus, Rhipicephalus turanicus) and repellent (anti-feeding) efficacy against tick infestations (Ixodes ricinus) for 8 months. It is effective against larvae, nymphs and adult ticks.
Ticks already on the cat prior to treatment may not be killed within 48 hours after collar application and may remain attached and visible. Therefore removal of ticks already on the cat at the time of application is recommended. If you are unsure how to safely remove ticks from your animal, seek professional guidance. The prevention of infestations with new ticks starts within two days after application of the collar.
Dogs
For the treatment (Ctenocephalides felis) and prevention of flea (Ctenocephalides felis, C. canis) infestation for 7 to 8 months.
Protects the animal’s immediate surroundings against flea larvae development for 8 months.
The product can be used as part of a treatment strategy for the control of Flea Allergy Dermatitis (FAD), where this has been previously diagnosed by a veterinary surgeon.
The product has persistent acaricidal (killing) efficacy against tick infestations (Ixodes ricinus, Rhipicephalus sanguineus, Dermacentor reticulatus) and repellent (antifeeding) efficacy against tick infestations (Ixodes ricinus, Rhipicephalus sanguineus) for 8 months. It is effective against larvae, nymphs and adult ticks.
Ticks already on the dog prior to treatment may not be killed within 48 hours after collar application and may remain attached and visible. Therefore removal of ticks already on the dog at the time of application is recommended. If you are unsure how to safely remove ticks from your animal, seek professional advice. The prevention of infestations with new ticks starts within two days after application of the collar.
The product provides indirect protection against the transmission of the pathogens Babesia canis vogeli and Ehrlichia canis from the tick vector Rhipicephalus sanguineus, thereby reducing the risk of canine babesiosis and canine ehrlichiosis for 7 months.
For treatment of biting/chewing lice (Trichodectes canis) infestation.
Contraindications
Do not treat kittens less than 10 weeks of age.
Do not treat puppies less than 7 weeks of age.
Do not use in case of hypersensitivity to the active substances or to any of the excipients.
Special warnings for each target species
Ticks will be killed and fall off the host within 24 to 48 hours after infestation without having had a blood meal, as a rule. An attachment of single ticks after treatment cannot be excluded. For this reason, a transmission of infectious diseases by ticks cannot be completely excluded if conditions are unfavourable.
Ideally, the collar should be applied before the beginning of the flea or tick season.
As with all long-term topical products, periods of excessive seasonal hair shedding may lead to transient slight reduction of efficacy by loss of hair-bound portions of the active ingredients. Replenishment from the collar starts immediately so that full efficacy will be re-established without any additional treatment or collar replacement. For optimum control of flea problems in heavily infested households it may be necessary to treat the environment with a suitable insecticide.
The product is water resistant; it remains effective if the animal becomes wet. However, prolonged, intense exposure to water or extensive shampooing should be avoided as the duration of activity may be reduced. Studies show that monthly shampooing or water immersion does not significantly shorten the 8 months efficacy duration for ticks after redistribution of the active substances in the coat whereas the product’s flea efficacy gradually decreased, starting in the 5th month.
Special precautions for use
Special precautions for use in animals
None.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
Keep the bag with the collar in the outer packaging until ready to use.
Immediately dispose of any remnants or off-cuts of the collar (see section 'Amounts to be administered and administration route').
Do not allow children to play with the collar, or to put it into their mouths.
Imidacloprid and flumethrin are continuously released from the collar onto the fur whilst the collar is being worn.
The product may cause hypersensitivity reactions in some people. People with known hypersensitivity (allergy) to the ingredients of the collar should avoid contact with the product.
The product may cause skin, eye and respiratory irritation in some people in very rare cases. Pets wearing the collar should not be allowed to sleep in the same bed as their owners, especially children.
Wash hands with cold water after fitting the collar.
Adverse reactions (frequency and seriousness)
Mild application site reactions such as pruritus (itchiness), erythema (redness) and hair loss may occur. These have been reported as uncommon and usually resolve within 1 to 2 weeks without the need for collar removal.
In single cases, a temporary collar removal may be recommended until the symptoms have disappeared.
In rare cases mild behavioural disorders that may include scratching at the application site may be observed in animals that are not used to wearing collars on the first few days after fitting. Ensure that the collar is not fitted too tightly.
Also in rare cases, slight and transient reactions such as depression, change of food intake, salivation, vomiting and diarrhoea might occur initially.
Cats
In rare cases, application site reactions such as dermatitis, inflammation, eczema or lesions may occur and in these instances, collar removal is recommended.
As with other topical applications, allergic contact dermatitis might occur in hypersensitive animals.
Dogs
In very rare cases, application site reactions such as dermatitis, inflammation, eczema or lesions may occur and in these instances, collar removal is recommended.
In rare cases neurological symptoms as ataxia, convulsions and tremor may occur. In these cases collar removal is recommended.
The frequency of adverse reactions is defined using the following convention:
very common (affects more than 1 animal in 10)
common (affects 1 to 10 animals in 100)
uncommon (affects 1 to 10 animals in 1,000)
rare (affects 1 to 10 animals in 10,000)
very rare (affects less than 1 animals in 10,000)
Use during pregnancy, lactation or lay
Laboratory studies with either flumethrin or imidacloprid in rats and rabbits have not produced any effects on fertility or reproduction and showed no teratogenic, or foetotoxic effects. However, the safety of the veterinary medicinal product has not been established in target animals during pregnancy and lactation and in the absence of available data, the product is therefore not recommended in pregnant and lactating queens or bitches.
Interaction with other medicinal products and other forms of interaction
None known.
Amounts to be administered and administration route
Cutaneous use. One collar per animal to be fastened around the neck.
Cats receive one collar of 38 cm length.
Small dogs up to 8 kg body weight receive one collar of 38 cm length.
Dogs above 8 kg receive one collar for dogs > 8 kg of 70 cm length.
For external use only.
Remove collar from protective bag directly before use. Unroll collar and make sure that there are no remnants from the plastic connectors inside the collar. Adjust the collar around the animal's neck without tightening it too tight (as a guide, it should be possible to insert 2 fingers between the collar and the neck). Pull excess collar through the loop and cut off any excess length extending beyond 2 cm.
Fitting the collar to the cat (see diagram)
Description: Seresto cat picture BIG
Fitting the collar to the dog (see diagram)
Description: Seresto dog picture BIG
The collar should be worn continuously for the 8 month protection period and should be removed after the treatment period. Check periodically and adjust fit if necessary, especially when kittens and puppies are rapidly growing.
Cat
Seresto Flea and Tick Control 1.25 g + 0.56 g, collar for cats is designed with a safety-closure mechanism.
Overdose (symptoms, emergency procedures, antidotes), if necessary
Due to the nature of the collar overdosage is unlikely and signs of overdosage are not to be expected.
In the unlikely event of the animal eating the collar mild gastrointestinal symptoms (e.g. loose stool) may occur.
Cat
An overdosage of 5 collars around the neck was investigated in adult cats for an 8 month period and in 10 week old kittens for a 6 month period and no adverse effects were observed other than those already described in section 'Adverse reactions'.
Dog
An overdosage of 5 collars around the neck was investigated in adult dogs for an 8 month period and in 7 week old puppies for a 6 month period and no adverse effects were observed besides slight hair loss and mild skin reactions.
Withdrawal period(s)
Not applicable.