One ml of solution contains:

Hydrocortisone aceponate 0.584 mg

Equivalent to 0.460 mg of hydrocortisone

For the full list of excipients, see pharmaceutical particulars

Cutaneous spray, solution.

Clear colourless to slightly yellow solution.

Pharmacotherapeutic group: Corticosteroids, dermatological preparations.
ATC vet code: QD07AC16.

Pharmacodynamic properties
The veterinary medicinal product contains the active substance hydrocortisone aceponate. Hydrocortisone aceponate is a dermocorticoid with a potent intrinsic glucocorticoid activity which means a relief of both inflammation and pruritus leading to a quick improvement of skin lesions observed in case of inflammatory and pruritic dermatosis.

Pharmacokinetic particulars
Hydrocortisone aceponate belongs to the diesters class of the glucocorticosteroids. The diesters are lipophilic components ensuring an enhanced penetration into the skin associated to a low plasma availability. Hydrocortisone aceponate thus accumulates in the dog’s skin allowing local efficacy at low dosage. The diesters are transformed inside the skin structures. This transformation is responsible for the potency of the therapeutic class. In laboratory animals, hydrocortisone aceponate is eliminated the same way as hydrocortisone (other name for endogenous cortisol) through urine and faeces. Topical application of diesters results in high therapeutic index: high local activity with reduced systemic secondary effects.

Propylene glycol methyl ether.

None known.

Shelf life of the veterinary medicinal product as packaged for sale: 2 years.
Shelf life after first opening the immediate packaging: 6 months.

Do not store above 25°C.

White polyethylene terephthalate (PET) bottle closed with a white polypropylene screw cap with bore seal and supplied with a spray pump. Cardboard box containing 1 bottle of 76 ml.

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.

Ecuphar NV,
Legeweg 157-i
B-8020
Oostkamp
Belgium

UK (GB) Vm 32742/5000

Date of first authorisation: 27/08/2018