Pharmacodynamic properties
Ketoprofen is a derivative of phenylpropionic acid, and belongs to the non steroidal anti-inflammatory group of drugs. Like all such substances, its principal pharmacological actions are anti-inflammatory, analgesic and anti pyretic. The mechanism of action is related to the ability of ketoprofen to interfere with the synthesis of prostaglandins from precursors such as arachidonic acid.
Following intravenous injection in the horse, the onset of musculo-skeletal antiinflammatory activity occurs by 2 hours, and reaches a peak at about 12 hours. It is still measurable 24 hours after each dose.
Pharmacokinetic particulars
Ketoprofen binds 95% to plasma proteins.
Major incompatibilities
In the absence of compatibility studies, this veterinary medicinal product must not be mixed with other veterinary medicinal products.
Shelf life
Shelf-life of the veterinary medicinal product as packaged for sale: 3 years
Shelf-life after first opening the immediate packaging : 28 days
Special precautions for storage
Do not refrigerate or freeze.
Keep the vial in the outer carton in order to protect from light.
Nature and composition of immediate packaging
The product is packed in amber type II glass vials of 50 ml or 100 ml, fitted with red chlorobutyl stoppers and aluminium caps.
Not all pack sizes may be marketed.
Special precautions for the disposal of unused veterinary medicinal product or waste materials derived from the use of such products
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements