Pharmacotherapeutic group: Immunologicals for Suidae, inactivated bacterial vaccines for pigs, clostridium.

ATCvet code: QI09AB12.

The active immunisation of pregnant sows and gilts induces the production of neutralising antibodies against Clostridioides difficile, toxins A and B and Clostridium perfringens type A, α-toxin. These antibodies are transferred via the colostrum to the piglets. The uptake of sufficient colostrum within the first hours of life results in a passive protection of piglets.

Efficacy of the vaccine was demonstrated upon intraperitoneal challenge with C. difficile toxin A and B and alpha toxin from C. perfringens type A. The efficacy of the vaccine to reduce the occurrence of diarrhoea was demonstrated under field conditions.