IMMUNOLOGICAL INFORMATION
ATCvet code: QI02AH
To stimulate active immunity against bovine respiratory syncytial virus (BRSV), bovine herpesvirus type 1 (BoHV-1), bovine parainfluenza 3 virus (PI-3) and bovine viral diarrhoea virus types 1 and 2 (BVDV-1 and BVDV-2).
The duration of immunity of one year after re-vaccination for BRSV and PI-3 is based on results of serological studies.
For bovine herpesvirus type 1, vaccinated animals can be differentiated from field virus infected animals, due to the marker deletion (gE-), by means of commercial diagnostic kits.
For BVDV, the vaccine only contains the immunogenic glycoprotein E2, present in BVDV-1 and BVDV-2. Hence, since vaccination does not induce the production of antibodies against any other protein present in BVDV-1 and BVDV-2 different from E2 (marker vaccine), vaccinated animals can be differentiated from field virus infected animals by means of commercial diagnostic kits.