For subcutaneous use.
Dosage is 0.5 ml/50 kg bodyweight, equivalent to 1.0 mg moxidectin/kg bodyweight, given by a single subcutaneous injection in the ear using an 18 gauge, 25 – 40 mm hypodermic needle. The 50 ml vial stoppers must not be broached more than 20 times. Use automatic syringe equipment for the 250 ml vial, no more than five piercings should be made.
Shake well before use.
Underdosing could result in ineffective use and may favour resistance development. To ensure that the correct dosage is used, an animal’s bodyweight should be determined as accurately as possible. If animals are to be treated collectively, reasonably homogeneous groups should be set up, and all animals in a group should be dosed at a rate corresponding to the heaviest one.
Accuracy of the dosing device should be thoroughly checked.
The injection should be given subcutaneously in the loose tissues on the dorsal surface of the ear, just distal to the distal edge of the auricular cartilage.
The dorsal (outer) surface of the ear should first be cleansed with antiseptic and allowed to briefly air dry. Palpate the edge of the auricular cartilage closest to the head, on the dorsal (hairy) surface of the ear. From this landmark, taking care to avoid blood vessels (artery, vein), the needle should be inserted subcutaneously starting at a point approximately 3 to 3.5 cm distal to this edge (away from the head), and directed towards the base of the ear, and the needle advanced to the hub. At this point, gently aspirate the syringe to confirm that the needle is not in a blood vessel.
Upon injection, the resulting depot should reside just distal to the edge of the auricular cartilage.
Following administration, the needle is withdrawn from the skin as pressure is applied for several seconds with the thumb at the point of insertion.
Due to the long-lasting protection against Dictyocaulus viviparus and the stomach worms, Ostertagia ostertagi and Haemonchus placei, a single treatment with the formulation at turn-out helps control parasitic bronchitis (lungworm) and parasitic gastro-enteritis throughout the grazing season by reducing the build-up of infective larvae on pasture associated with these parasites.
For best results the injection should be given to each calf of target weight to be grazed together immediately prior to being turned out to pasture. Animals should be set stocked throughout the grazing season or moved to a pasture which has not been grazed by other cattle earlier in the season.
Diagram: Ear injection procedure.
∙ The injection site is approximately 3.5 cm (1.5 inches) distal to the distal edge of the auricular cartilage.
∙ Use one hand to grasp and steady the ear.
∙ Inject subcutaneously using an 18 gauge x 1 inch needle.
∙ Inject contents. Depot should be just distal to the distal edge of the auricular cartilage.
∙ Apply pressure at the point of insertion as the needle is withdrawn from the skin to help seal the opening.