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Contra-indications, warnings, etc
Contraindications
Do not use with the following tropical fish species:
Apistogramma (Mikrogeophagus) ramirez, Balantiocheilos melanopterus, Etroplus suratensis, Melanotaenia maccullochi, Monodactylus argenteus, Phenacogrammus interruptus and Scatophagus argus.
Special precautions for use
Special precautions for use in animals
Do not exceed the dose recommended for each category of fish. Brood stock anaesthetised for stripping should be immersed in unmedicated water immediately before collection of eggs or milt to avoid significant direct contact of either with the product.
As solutions of the veterinary medicinal product are slightly acidic, the use of phosphate or imidazole buffer has been proposed to reduce stress.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
People with known hypersensitivity to tricaine methanesulfonate should avoid contact with the veterinary medicinal product.
Impermeable rubber gloves should be worn when handling the veterinary medicinal product.
Avoid contact with skin and eyes. In case of accidental contact, immediately wash the affected area with plenty of clean running water. If irritation persists, seek medical advice.
Do not create dust when handling the powder or preparing the anaesthetic solution. In case of accidental inhalation of dust, move to fresh air and if breathing is affected, seek medical advice immediately and show the package leaflet or the label to the physician.
In situations where dust is created when handling the product, wear a disposable half mask respirator conforming to European Standard EN 149 or a non-disposable respirator to European Standard EN 140 with a filter to EN 143.
Do not eat, drink or smoke whilst handling this product.
Wash hands after use
In case of accidental ingestion, seek medical advice immediately and show the package leaflet or the label to the physician.
Other Precautions
In order to protect the environment, used solution must either be filtered using activated charcoal filters prior to dilution in the effluent to be discharged from the farm or it must be transferred to a holding tank filled with water with subsequent controlled release for dilution in the effluent to be discharged from the farm.
Special precautions for the disposal of unused veterinary medicinal product or waste materials derived from the use of such products
Used solution must either be filtered using activated charcoal filters prior to dilution in the effluent to be discharged from the farm or it must be transferred to a holding tank filled with water with subsequent controlled release for dilution in the effluent to be discharged from the farm.
Transfer of used solution to a holding tank filled with water and controlled release for dilution in effluent will ensure that the concentration of spent tricaine methanesulfonate in discharge water does not exceed 1 μg·L-1. When releasing the solution from the holding tank, flow rates are calculated based on the following equation:
Discharge (L/hr ) = Farm flow rate (L/min)×0.90 (safety factor)
Holding tank concentration (mg/L )×1000 × 60
Eg. Holding tank concentration (mg/L)
Farm flow rate (L/min)
Discharge flow from holding tank (L/h)
10
10,000 / 20,000 / 30,000
54 / 110 / 160
50
10,000 / 20,000 / 30,000
11 / 22 / 32
100
10,000 / 20,000 / 30,000
5.4 / 11 / 16
200
10,000 / 20,000 / 30,000
2.7 / 5.4 / 8.1
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.
Adverse reactions (frequency and seriousness)
None known.
Use during pregnancy, lactation or lay
Not applicable.
Interaction with other medicinal products and other forms of interaction
None known.
Overdose (symptoms, emergency procedures, antidotes), if necessary
Remove fish immediately to aerated water of the same composition and temperature that is free from anaesthetic. Overdose or prolonged exposure to the product may cause respiratory failure and death.