ATCvet code: QJ01DD90
Third-generation cephalosporins.
The veterinary medicinal product contains sodium ceftiofur, a broad-spectrum cephalosporin which is active against Gram-positive and Gram-negative bacteria, including beta-lactamase producing strains.
Ceftiofur has bactericidal activity in vitro. The mode of action is that of cephalosporins, i.e. inhibition of the bacteria cell wall synthesis.
After intramuscular administration ceftiofur is quickly metabolized to desfuroylceftiofur which reaches its maximum plasma concentration within 1 hour. The half-life of desfuroylceftiofur is on average greater than 9 hours in cattle and 13 hours in pigs. No accumulation has been shown after several administrations.