Target species
Cats.
Indications for use, specifying the target species
For the treatment of tapeworms of cats. The product is effective against mature and immature forms of Dipylidium caninum and Taenia species. The product is also effective against Echinococcus multilocularis.
Contraindications
Do not use on cats weighing less than 1 kg bodyweight.
Special warnings for each target species
Do not allow recently treated animals to groom each other.
Special precautions for use
Special precautions for safe use in the target species:
Care should be taken to avoid the contents of the tube coming into contact with the eyes or mouth of the user or recipient animal.
For external use only.
Special precautions to be taken by the person administering the veterinary medicinal product to animals:
Laboratory studies in rabbits and rats with the excipient N-methyl pyrrolidone have shown evidence of foetotoxic effects. The veterinary medicinal product should not be administered by pregnant women and women suspected of being pregnant.
Personal protective equipment consisting of gloves should be worn when handling the veterinary medicinal product by women of childbearing age.
This veterinary medicinal product can be an irritant to the skin and eyes.
Care should be taken to prevent contact of the solution with the skin or eyes.
In case of accidental spillage onto skin, wash off any skin contamination with soap and water immediately.
If accidental contact occurs with the eyes, flush the affected eyes thoroughly with clean fresh water.
In case of accidental contact with the eyes or skin, seek medical advice and if irritation persists show the package leaflet or the label to the physician.
Do not stroke or groom animals until area of application is dry (typically around 1 hour after application).
Wash hands thoroughly after use.
Do not eat, drink or smoke during application.
Store away from food, drink or animal feeding stuffs.
Special precautions for the protection of the environment:
Not applicable.
Adverse events
Cats:
Very rare (<1 animal / 10,000 animals treated, including isolated reports): | Application site reaction1 (e.g. dandruff1, exudation1,2, hair loss1, reddening1, itching1, scab1) Hypersalivation3 |
1 Transient
2 Mild
3 Due to the bitter taste of the product if the cat licks the application site immediately after treatment. This is not a sign of intoxication and disappears after a short time without treatment.
Reporting adverse events is important. It allows continuous safety monitoring of a veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to either the marketing authorisation holder or the national competent authority via the national reporting system. See the package leaflet for respective contact details.
Use during pregnancy, lactation or lay
The safety of the veterinary medicinal product has not been established during pregnancy, lactation or in animals intended for breeding.
Pregnancy and lactation:
Laboratory studies in rabbits and rats with the excipient N-methylpyrrolidone have shown evidence of foetotoxic effects.
Use only according to the benefit-risk assessment by the responsible veterinarian.
Interaction with other medicinal products and other forms of interaction
None known.
Administration routes and dosage
Dosage and Treatment Schedule:
To ensure a correct dosage, body weight should be determined as accurately as possible to avoid underdosing.
The minimum dose rate is 8 mg/kg bodyweight, which equates to 1 tube per 2.5 kg bodyweight.
Bodyweight | Number of Tubes | Quantity of Praziquantel | mg/kg bw |
1 - 2.5 kg | 1 | 20 mg | 8 - 20 |
>2.5 - 5 kg | 2 | 40 mg | 8 - 16 |
>5 kg | 3 | 60 mg | maximum 12 |
Underdosing could result in ineffective use and may favour resistance development.
Method of Administration
Remove one tube from the package. Hold tube in an upright position, twist and pull off cap. Use reversed cap to twist and remove seal from tube.
Part the hair on the cat's neck at the base of the skull until the skin is visible.
Place the tip of the tube on the skin and squeeze firmly several times to empty the contents directly onto the skin. Application at the base of the skull will minimise the opportunity for the cat to lick the veterinary medicinal product.
To minimise the possibility of run-off after application of more than one pipette, it is advised that the applications should be performed slowly to allow absorption and that it may be advisable to allow the contents of the previous pipette to be absorbed before applying another.
Tapeworm infestation is certain to re-occur unless control of intermediate hosts such as fleas, mice etc. is undertaken.
Flea control: flea infestations can be controlled by the regular use of effective flea control remedies.
Mice control: if cats roam and hunt, contact with, and consumption of, mice and subsequent re-infestation with Taenia taeniaeformis is impossible to prevent.
It is recommended to re-apply the product when signs of tapeworm infestation re-appear or at monthly intervals.
Symptoms of overdose (and where applicable, emergency procedures and antidotes)
Overdosing can lead to slight skin reactions which disappear without treatment within a few days.
Special restrictions for use and special conditions for use, including restrictions on the use of antimicrobial and antiparasitic veterinary medicinal products in order to limit the risk of development of resistance
Not applicable.
Withdrawal period(s)
Not applicable.