Significant change:Renewal (multiple changes): Name change from 'Eprinex Multi 5mg/ml pour-on for beef and dairy cattle, sheep and goats' to 'Eprinex Multi 5mg/ml pour-on solution for cattle, sheep and goats'. The following wording has moved from 'Special Precautions for use in Animals' to 'Contraindications' - "Avermectins can cause fatalities in dogs, especially Collies, Old English Sheepdogs and related breeds and crosses, and also in turtles/tortoises." In 'Other Precautions' the following text has been updated to "In order to reduce the risk to aquatic ecosystems, treated animals should not have direct access to water bodies for a minimum of two to five weeks after treatment." In 'Amounts to be administered and administration route' the wording "For single application only" has been added and "All the animals belonging to the same group should be treated at the same time." Multiple changes to the "Method of Administration" section under the 'For 250ml and 2litre bottles' and 'For 2.5 and 5 litre back-pack' headings to improve clarity. Addition of the following wording to "Environmental Properties" - "Eprinomectin is very toxic to aquatic organisms, is persistent in soils and may accumulate in sediments." The following wording has been added to Disposal Section "Extremely dangerous to fish and aquatic life".