Contraindications
None.
Special warnings for each target species
Vaccinate healthy animals only.
The vaccine has not been tested in breeding boars. Therefore, the vaccination of breeding boars is not recommended.
Do not vaccinate animals which are receiving treatment with antimicrobials effective against Lawsonia spp. Such antimicrobials should be withheld for a minimum of 3 days before and 3 days after the day of vaccination.
Efficacy of revaccination is unknown.
Special precautions for use
Special precautions for use in animals.
In case of anaphylactic reactions, appropriate symptomatic treatment including the administration of glucocorticoids, adrenaline, or antihistamines is recommended.
The vaccine is an attenuated live vaccine and the potential for spreading to non-vaccinated animals cannot be excluded. However, based on the studies conducted with sentinel pigs, the apparent frequency of spreading and associated risk is very low. Lawsonia intracellularis DNA could be detected up to 3 days post vaccination in faecal samples of more than half of vaccinated animals, therefore transmission to pen-mates cannot be excluded in this time period.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
Avoid accidental contact with the skin. In the event of accidental skin contact, wash with soap or antibacterial wash and rinse well.
Adverse reactions
None known.
Use during pregnancy, lactation or lay
No adverse reaction was observed after administration of the vaccine in breeding and pregnant animals.
Interaction with other medicinal products and other forms of interaction
Since the vaccine isolate is a live bacterium, simultaneous use of antimicrobials which are effective against Lawsonia spp. should be avoided for a minimum of 3 days before and after vaccination.
No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case-by-case basis.
Overdose
No adverse reactions have been observed following administration of 10 times the recommended dose.
Withdrawal period
Zero days.