Chanazine 10% is given by slow intravenous injection. Dosage is dependent on the degree of sedation required and the response of the animal, and is 0.5 – 1 ml/100 kg (0.5 - 1 mg/kg) bodyweight. Nervous or excitable horses may require higher doses. Older horses and those having undergone severe physical exertion before treatment should receive the lowest dose rate. Animals do not usually become recumbent after administration and light to deep sedation with a variable degree of analgesia is obtained. Effects are usually seen within 5 minutes and persist for approximately 20 minutes. Chanazine 10% may be employed as a premedication to barbiturate anaesthesia or in combination with regional or local anaesthesia.