Not for use in horses intended for human consumption.
Do not administer by the intra-carotid route.
Careful consideration should be given before administering to animals exposed to stress conditions such as extreme heat, cold, high altitude or fatigue.
Side Effects such as bradycardia, cardiac arrhythmia and polyuria may occur.
Following intravenous administration, a transient rise followed by a fall in blood pressure usually occurs. Should be used with caution when pulmonary disease is suspected.
Sedation is dose dependent and the occurrence of side effects will increase and worsen at higher dosage than recommended.
Chanazine 10% should not be administered in the later stages of pregnancy because of the risk of inducing premature parturition. As the safety of xylazine use during organogenesis has not been fully demonstrated by current methods it should be used with caution during the first month of pregnancy.
General precautions
For animal treatment only. Keep out of reach of children.
Operator warnings
Horses sedated with Xylazine usually remain standing and may still kick with accuracy.
Xylazine is an alpha adrenoceptor agonist acting primarily on alpha-2 receptors. Precaution should be taken to avoid accidental injection/self-injection. Wash splashes from skin and eyes immediately.
1. In the case of accidental oral intake or self-injection, seek medical advice immediately and show the package leaflet to the doctor but DO NOT DRIVE as sedation and changes in blood pressure may occur.
2. Avoid skin, eye or mucosal contact.
3. Immediately after exposure, wash the exposed skin with large amounts of fresh water.
4. Remove contaminated clothes that are in direct contact with skin.
5. In the case of accidental contact of the product with eyes, rinse with large amounts of fresh water. If symptoms occur, seek the advice of a doctor.
6. If pregnant women handle the product, special caution should be observed not to self inject as uterine contractions and decreased foetal blood pressure may occur after accidental systemic exposure.
7. Advice to Doctors: Xylazine is an alpha2-adrenoreceptor agonist. Symptoms after absorption may involve clinical effects including dose-dependent sedation, respiratory depression, brachycardia, hypotension, a dry mouth, and hyperglycaemia. Ventricular arrhythmias have also been reported. Respiratory and haemodynamic symptoms should be treated symptomatically.
Environmental warnings
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.
Withdrawal Periods
Not to be used in horses intended for human consumption.
Treated horses may never be slaughtered for human consumption.
The horse must have been declared as not intended for human consumption under national horse passport legislation.