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Pharmacological particulars
Pharmacotherapeutic group: Anti-inflammatory and antirheumatic products, non-steroids.
ATCvet code: QM01AA01
Pharmacodynamic properties
Phenylbutazone acts by inhibiting the production of prostaglandins. Prostaglandins possess a wide variety of physiological properties, including those involved in the production of pain, inflammation and pyrexia. The main metabolite, oxyphenbutazone, possesses similar pharmacological properties.
Pharmacokinetic properties
Phenylbutazone is generally well absorbed following oral administration. The rate, but not the extent, of absorption may be affected due to binding of phenylbutazone to food and the contents of the gastrointestinal tract. Therefore, it is recommended that Equipalazone Powder is administered mixed with a small amount of bran or oats. Phenylbutazone is highly bound to plasma proteins.