Pharmacotherapeutic group: Throat preparations, local anaesthetic, lidocaine
ATCvet code: QR02AD02
Pharmacodynamic properties
Lidocaine acts by preventing the generation and conduction of nerve impulses. It prevents the increase in permeability of excitable membrances to sodium ions. Small, non-myelinated nerve fibres are more susceptible than are large fibres and the sensation of pain is the first modality to be lost. The product has a duration of action of approximately 15 minutes.
Pharmacokinetic properties
Lidocaine is metabolised mainly in the liver and excreted via the kidneys. Approximately 95% is excreted via the form of various metabolites while 5% is excreted unchanged.