The product is administered sublingually at 40 mcg/kg. The dosing syringe delivers the product in 0.25 ml increments. The following dosing table provides the dose volume to be administered for the corresponding body weight in 0.25 ml increments.
Approximate body weight (kg)
Dose volume (ml)
150 - 199
200 - 249
250 - 299
300 - 349
350 - 399
400 - 449
450 - 499
500 - 549
550 - 600
Instructions for dosing: Apply impermeable gloves and remove the syringe from the outer carton. While holding the plunger, turn the ring-stop on the plunger until the ring is able to slide freely up and down the plunger. Position the ring in such a way that the side nearest the barrel is at the desired volume marking. Turn the ring to secure it in place.
Make sure that the horse’s mouth contains no feed. Remove the cap from the tip of the syringe and save the cap for replacement. Insert the syringe tip into the horse’s mouth from the side of the mouth, placing the syringe tip beneath the tongue at the level of the corner of the mouth. Depress the plunger until the ring-stop contacts the barrel, depositing the product under the tongue.
Take the syringe out of the horse’s mouth, recap the syringe and return it to the outer carton for disposal. Syringes should be used only once - partially used syringes must be discarded. Remove and discard gloves or wash them in copious quantities of running water.
After administration of the product, the animal should be allowed to rest in a quiet place for approximately 30 - 40 minutes to allow sedation to fully develop before any procedure is initiated.
Should there be a substantial misdosing or swallowing of the product (e.g. the horse spits out or swallows more than an estimated 25% of administered dose), immediate replacement dosing of the lost portion should be attempted with care to avoid accidental overdosing. For animals in which the administered dose results in inadequate duration of sedation to complete the intended procedure, re-administration of the product during the procedure may not be practical since transmucosal absorption is too slow to top-up the sedation. In such cases, a lip twitch may facilitate restraint. Alternatively, a veterinarian can administer additional injectable sedatives according to their clinical discretion.