The active substance of the product is detomidine. Detomidine is an alpha-2 adrenoceptor agonist with a central effect inhibiting the transmission of noradrenalin-mediated nervous impulses. In the animal, the level of consciousness is lowered and the pain threshold is increased. The duration and level of sedation are dose dependent. In the studies conducted with the recommended 40 mcg/kg dose of the gel, the time to onset of sedation has been approximately 30-40 min and the duration of sedation 2 to 3 hours.
Further information is available in the Summary of Product Characteristics