Do not administer to animals with known sulphonamide hypersensitivity.
Chickens and Turkeys: where appetite is depressed the inclusion rate should be increased to achieve the correct dosage.
To avoid possible crystalluria, adequate water intake is essential. Particular care is needed with animals suffering from renal damage.
When incorporated at a rate of below 2kg per tonne of animal feed, the product must only be mixed by a manufacturer who is approved to mix at that level.
Hypersensitivity to sulphonamides has been rarely reported, however this remains a potential undesirable effect. Crystalluria caused by precipitation of insoluble sulphonamide is a theoretical risk although rarely reported.
As there is no specific antidote, in case of overdose, treatment should be symptomatic.
Use during pregnancy, lactation or lay
Data on the exact level below which no effects on foetal development were observed are not available. However extensive use of the product in different species over many years, have not shown adverse effects on the foetus.
When administered to lactating females, small amounts of trimethoprim and sulfadiazine are present in the maternal milk. Since no studies have been reported of the effect on the development of new born young of the ingestion of this milk, it would be prudent not to feed very young animals with milk obtained from the mother.
Pigs- Meat: 5 days
Chickens- Meat: 1 day
Turkeys- Meat: 3 days
Do not administer to birds producing eggs intended for human consumption.